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Influenza Report 2006.pdf

August 19, 2009 · Filed Under Medical Textbook  · Tags: , , ,

Taken from Chapter 1: Influenza 2006 (Bernd Sebastian Kamps and Gustavo Reyes-Ter·n): Influenza pandemics resemble major natural disasters: we know there will be another one, but we ignore both time and magnitude. In most other aspects, they are different. Earthquakes in Tokyo or San Francisco last from seconds to a couple of minutes pandemics spread around the world in successive waves over months or a couple of years. And quite different are the consequences: an influenza pandemic may be a thousand times more deadly than even the deadliest tsunami.

As unpredictable as influenza pandemics are, as unpredictable is the virus itself. We know nothing about the pathogenic potential of the next pandemic strain. The next pandemic may be relatively benign, as it was in 1968 and 1957, or truly malignant, as was the 1918 episode. We donít know if the next pandemic will be caused by the current bÍte noire, H5N1, or by another influenza strain. We ignore how the next pandemic will evolve over time, how rapidly it will spread around the world, and in how many waves. We donít know which age groups are at the highest risk of severe outcomes. We have no idea whether the next pandemic will kill 2, 20, or 200 million people.

Not surprisingly, healthcare professionals are becoming sensitised to the risk of a new pandemic. The ongoing outbreak of H5N1 influenza among birds with occasional transmission to human beings is of major concern because of intriguing parallels between the H5N1 virus and the 1918 influenza strain. Should H5N1 acquire the capability of easy human-to-human transmissibility, even the most conservative scenario anticipates up to several 100 million outpatient visits, more than 25 million hospital admissions and several million deaths globally (WHO Checklist 2005).

It is wise to imagine and plan for the worst when facing an unknown threat. As the threat is global, strategies must be global ñ a tricky task when our planet is divided into more than two hundred nations. Dealing with nations and their leaders is like dealing with children in a kindergarten. In this difficult context, the WHO is performing an astonishing job.

In the following paragraphs, we shall take a look at the various facets of the war on influenza: the global and individual impact of the disease, the virus itself, and the individual and global management of what may one day turn out to be one of the most challenging healthcare crises in medical history. The most important thing to remember when talking about pandemic influenza is that its severe form has little in common with seasonal influenza. Pandemic influenza is not business-as-usual influenza. Bear this in mind. You wouldnít call a tiger a cat.

Contents:

  • Chapter 1: Influenza 2006 [ Global Impact ~ Individual Impact ~ The Virus ~ Individual Management ~ Global Management ~ Golden Links ~ Interviews ~ References ]
  • Chapter 2: Avian Influenza [ The Viruses ~ Natural hosts ~ Clinical Presentation ~ Pathology ~ Differential Diagnosis ~ Laboratory Diagnosis ~ Transmission ~ Economic Consequences ~ Control Measures against HPAI ~ Vaccination ~ Pandemic Risk ~ Conclusion ~ References ]
  • Chapter 3: Virology of Human Influenza [ Structure ~ Replication cycle ]
  • Chapter 4: Pathogenesis and Immunology [ Introduction ~ Pathogenesis ~ Immunology ~ Conclusion ]
  • Chapter 5: Pandemic Preparedness [ Introduction ~ Influenza Pandemic Preparedness ~ Inter-Pandemic Period and Pandemic Alert Period ~ Pandemic Period ~ Conclusions ~ References ]
  • Chapter 6: Vaccines [ Introduction ~ Vaccine Development ~ Efficacy and Effectiveness ~ Side Effects ~ Recommendation for Use ~ Companies and Products ~ Strategies for Use of a Limited Influenza Vaccine Supply ~ Pandemic Vaccine ~ References ]
  • Chapter 7: Laboratory Findings [ Introduction ~ Laboratory Diagnosis of Human Influenza ~ Laboratory Tests ~ Differential diagnosis of flu-like illness ~ New developments and the future of influenza diagnostics ~ Conclusion ~ Useful Internet sources relating to Influenza Diagnosis ~ References ]
  • Chapter 8: Clinical Presentation [ Uncomplicated Human Influenza ~ Complications of Human Influenza ~ Avian Influenza Virus Infections in Humans ~ References ]
  • Chapter 9: Treatment and Prophylaxis [ Introduction ~ Antiviral Drugs ~ Treatment of 'Classic' Human Influenza ~ Treatment of Human H5N1 Influenza ~ Transmission Prophylaxis ~ Global Pandemic Prophylaxis ~ Conclusion ~ References ]
  • Chapter 10:Drug Profiles [ Amantadine ~ Oseltamivir ~ Rimantadine ~ Zanamivir ]

This health ebook is available FREE at Influenza Report website, we merely collect the information, we are neither affiliated with the author(s), the website and any brand nor responsible for its content and change of content. (Read our disclaimer here or here before you download the document from the website written above by clicking the below link).

Download free Influenza Report 2006.pdf (36 pages pdf file, 2.7 MB).

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