Genetics.pdf



This course material covers the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Topics inside this pdf material include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.

Contents:

  • Physical Structure of the Gene
  • The Complementation Test and Gene Function
  • Mendelian Genetics
  • Probability and Pedigrees
  • Chromosomes and Sex Linkage
  • Recombination and Genetic Maps
  • Three-factor Crosses
  • Tetrad Analysis
  • Phage Genetics
  • Gene Structure and DNA Analysis
  • Mutations and Suppressors
  • Bacterial Genetics: Transposition
  • Bacterial Genetics: Transduction
  • Complementation in Bacteria: Plasmids
  • Complementation in Bacteria: Recombinant DNA
  • Prokaryotic Regulation: Negative Control
  • Prokaryotic Regulation: Positive Control
  • Prokaryotic Regulation: Regulatory Circuits
  • Eukaryotic Genes and Genomes I
  • Eukaryotic Genes and Genomes II
  • Eukaryotic Genes and Genomes III
  • Eukaryotic Genes and Genomes IV
  • Transgenes and Gene Targeting in Mice I
  • Transgenes and Gene Targeting in Mice II
  • Population Genetics: Hardy-Weinberg
  • Population Genetics: Mutation and Selection
  • Population Genetics: Inbreeding
  • Human Polymorphisms
  • Statistical Evaluation of Linkage I
  • Statistical Evaluation of Linkage II
  • Complex Traits
  • Chromosome Anomalies I
  • Genetics of Cancer I
  • Genetics of Cancer II

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